To control hyperglycemia in metformin responsive stable, mild, nonketosis prone, maturity onset type of diabetes (Type Il) which cannot be controlled by proper dietary management, exercise and weight reduction or when insulin therapy is not appropriate. Metformin can be of value for the treatment of obese diabetic patients.
Contra-Indications
Unstable and/or insulin-dependent (Type I) diabetes mellitus, history of ketoacidosis with or without coma. In the presence of severe liver disease. In the presence of renal impairment or when renal function is not known, and also in patients with serum creatinine levels above the upper limit of the normal range. – In chronic alcoholism with hepatic damage. – In patients undergoing medical or diagnostic examinations, such as i.v. pyelography or angiography which could lead to temporary functional oliguria. In cases of cardiovascular collapse and in disease states associated with hypoxemia such as cardiorespiratory insufficiency, which are often associated with hyperlactacidemia. In patients suffering from severe dehydration. – During stress conditions, such as severe infections, trauma or surgery and the recovery phase thereafter. – Known sensitivity or allergy to the drug. In patients with a history of lactic acidosis irrespective of the precipitating factors.
Dosage Forms:
Diabin-500mg Tablets:
Each tablet contains: Metformin HCI BP…… 500mg.